About POLARIS

Mission

POLARIS — the Platform for Omics, Longevity and Aging Biomarker Insights — is the front door to the Higgins-Chen Lab's aging-biomarker platform. It unifies a growing set of independent tools under one roof, so researchers can move seamlessly from discovering which biomarkers exist, to understanding the biology they capture, to seeing what the studies found, to judging which biomarkers actually perform.

A question-driven framing

The platform is organized as a compass. Four questions point the way, and each maps onto a tool:

1. 1

   “What happened in the studies?”

   CpG Library — manuscripts on datasets, biomarkers, DNAm biology

2. 2

   “Which biomarkers perform well?”

   TranslAGE — stability, treatment response, associations, risk prediction

3. 3

   “What biomarkers exist?”

   methylCIPHER — algorithms, coefficients, and metadata

4. 4

   “What biology do these biomarkers capture?”

   CpG Atlas — biological, functional, technical properties

Tying it together, HarmonyAgent continually discovers, curates, and integrates new knowledge across the platform — so the compass always points at the current state of the field.

Attribution

POLARIS is developed by the Higgins-Chen Lab. The platform's methods and findings are documented across our publications. This hub is an informational portal: it introduces each tool and routes you to it. Text and figures on this page are placeholders where lab- provided copy is pending.